Which substance is released by the stomach when food is ingested?

Study for the HESI A2 28 Anatomy and Physiology Exam. Explore in-depth questions with hints and explanations. Master the material to ensure success on your exam day!

The release of hydrochloric acid from the stomach upon food ingestion plays a crucial role in the digestive process. Hydrochloric acid creates an acidic environment in the stomach, which is essential for activating digestive enzymes, including pepsin. This strong acid also helps in breaking down food particles and provides a hostile environment for pathogens that may have been ingested with food.

Furthermore, hydrochloric acid aids in converting pepsinogen, an inactive enzyme secreted by the stomach lining, into pepsin, an active enzyme essential for protein digestion. The acidic environment also facilitates the breakdown of connective tissues in meat and aids in the overall digestion process. This ensures that nutrients can be more readily absorbed as they progress through the digestive system.

The other substances listed do not play the same direct role in the initial response to food ingestion in the stomach. Sodium chloride may contribute to the ionic composition of gastric secretions but is not specifically released in response to food. Pepsin, while essential, is activated by hydrochloric acid rather than being the first substance released itself. Hydrochloric bicarbonate does not accurately represent a substance produced by the stomach during digestion.

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